CTMC2011 »  Clustering within Trials

Session: Clustering within Trials and Cluster RCTs

Clustering is commonly encountered in pragmatic trials, in both cluster and individually randomised controlled trials.


- review and discuss how we can account for therapist and group effects within the context of individually randomised controlled trials

- identify sources of clustering and how these should be accounted for in the design and analysis of both types of trials

- consider advances in the sample size estimation of cluster randomised trials, including how to deal with variation in cluster size within the sample

Oral Presentations

Click on the links below to view the presentations.

Statistical issues in the analysis of non-pharmacological therapy trials with clustering by care-provider or therapy group

Stratified randomisation: a hidden form of clustering?

The analysis of an individually randomised clinical trial of back pain with clustering effect due to group sessions and repeated measures

A review of methodology for sample size calculations in cluster randomised trials